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Larazotide research vial from ZestyRat Research

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CapsulesRecovery & Repair

Larazotide

Tight-junction regulator studied specifically for intestinal permeability. 350mcg, 60 capsules.

For research use only · not for human consumption

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Larazotide
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Independent research on Larazotide. Our sister publication Peptides Uncaged maintains a plain-English research guide covering mechanism, the published literature, and how vendors are scored on purity and COA transparency. It is written independently of any lab. How to read a COA is worth ten minutes before your first order.
The research

What Larazotide is being studied for

Larazotide acetate (formerly AT-001, Alba Therapeutics) is an oral peptide derived from the zonula occludens toxin secreted by Vibrio Cholera. As a tight junction regulator, it binds to receptors of apical intestinal cells and prevents opening of epithelial intestinal tight junctions induced by bacterial antigens, pro-inflammatory cytokines, or gliadin peptides.

Its mechanism has been supported by in vitro and in vivo studies, making it a suitable candidate to treat celiac disease. Larazotide acetate aids in the restoration of the intestinal barrier function by intervening in the zonulin-mediated signaling pathway, blocking zonulin receptors, preventing tight junction disassembly, and minimizing the increase in intestinal permeability.

Moreover, larazotide acetate is involved in rearranging several tight junction proteins to promote tight junction assembly. Larazotide acetate also plays a role in stimulating tight junction closure. BOTTLE DESIGN MAY VARY LARAZOTIDE COA.

Summary of published preclinical and clinical literature, provided for research context only. Not a claim of efficacy and not medical advice.

Common questions

Larazotide — FAQ

What is Larazotide?

Tight-junction regulator studied specifically for intestinal permeability. 350mcg, 60 capsules.

What formats does Larazotide come in?

ZestyRat Research supplies Larazotide as capsules. Available options: Single unit at $75.

Is there a certificate of analysis for Larazotide?

Yes. ZestyRat Research is our top-rated research supplier and provides a certificate of analysis on every batch. A COA reports identity by mass spectrometry and purity by HPLC — if you are not sure how to read one, our guide on reading a certificate of analysis walks through it line by line.

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Why we send everyone to one supplier

While we build, we buy from ZestyRat Research.

Our own line is in development. Until it is finished this site does one job: send you somewhere we would order from ourselves. That is ZestyRat, and it is not a close call — 47 orders have been placed through our links, 30 of them in the last month, and every order that cleared checkout has shipped. Not one has gone missing.

Speed
ZestyRat states orders placed before 3pm ET ship the same day; their shipping policy commits to the next business day. USPS Priority or UPS, 1-3 business days.
Testing
Independently tested, 99%+ purity, per ZestyRat's own published standard.
Tracking
Tracking on every order, in plain packaging with no external labelling. All 50 US states, DC and US territories — they do not ship internationally.
Price
Consistently at or under the market on the compounds researchers buy most.
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Ratings on this page are our own editorial assessment, based on published COA practice, checkout and shipping experience, and price tracking. We earn a commission on orders placed through our links, at no extra cost to you. Research use only.

How we review suppliers

CD Biolab is an independent research library. We do not manufacture, stock, price, test or ship anything. We review suppliers on their published testing standards, reputation, fulfilment record and pricing, and the ratings we publish are our own editorial assessment. Product photography on this site is © ZestyRat Research and is shown to identify the products they sell — not to represent stock held by CD Biolab.

Every compound referenced on this site is sold by its vendor strictly as a research chemical for in-vitro laboratory research only — not for human or animal consumption, and not intended to diagnose, treat, cure or prevent any disease. Nothing here is medical advice. We earn a commission on orders placed through our links, at no additional cost to you; all material connections are disclosed in line with FTC guidelines.

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